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When incoming impulses are completely prevented from reaching the 2nd stage nerves, these nerves react by rapidly increasing their excitability. Without any incoming messages as a result of amputation or nerve transection, the other stage nerves learn to fire off spontaneously, that may be for no particular reason but because they are over-excited. The leg nerves may be missing but the many nervous system transmission nerves for the shin bone survive. The areas of as their pharmicudical counterpart caring for the missing part remain present whilst still being able to creating pain for the reason that missing part.Medications are usually put into two groups - non-prescription (OTC) medications, which are available in pharmacies and supermarkets without special restrictions, and prescription only medicines (POM), which has to be determined by a physician. A lot of the OTC medications are often considered safe enough as they don't harm people if taken as instructed.
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